Neuromodulation for Brain and Spinal Cord Functional Restoration in Neurological Disorders

Hosted by AR3T and NC NM4R


Description: This workshop introduced methods for targeted neuromodulation as an adjunct to regenerative rehabilitation approaches.. The intended audience is diverse, for scientists and clinicians with backgrounds in a range of sciences such as nervous system injury, regenerative rehabilitation, neuromodulation, and clinical practices such as physiatry, neurology, and surgical specialties. Examples of neuromodulation introduced included:

  • Transcranial magnetic stimulation (TMS) including high-rate stimulation for long-lasting changes in regional brain function (e.g. in treatment of depression.)
  • Multimodal transcranial magnetic stimulation (e.g., combined with EEG, fMRI, transcranial focused ultrasound)
  • Transcranial direct current stimulation (tDCS) and its use in the treatment of stroke, traumatic brain injury, psychiatric disorders, primary progressive aphasia, etc.
  • Transcutaneous vagus nerve stimulation for increasing plasticity and learning

Dr. Jon Wolpaw directly addressed the importance of merging regenerative rehabilitation and neuromodulation as he discussed operant conditioning of evoked responses as a potential way to train new neural circuits generated regenerative medicine techniques.

Attendees participated in an incubator session with 1-slide pitch talks to launch conversation and generate ideas. This exercise resulted in the opportunity to apply for a scholarship to support new, interdisciplinary collaboration between regenerative medicine and neuromodulation researchers.

2:00-2:10pm EST Welcome, Introduction
Rick Segal, PT, PhD, FAPTA
Medical University of South Carolina, Charleston, SC
2:15-2:30pm EST How Regenerative Rehabilitation Can Benefit from Neuromodulation
Franklin West, PhD
University of Georgia, Athens, GA
2:30-2:55pm EST A Brief Introduction to Neuromodulatory Techniques including Transcranial Magnetic Stimulation
George Wittenberg, MD, PhD
University of Pittsburgh, Pittsburgh, PA
2:55-3:05pm EST Transcutaneous Auricular Vagus Nerve Stimulation
Bashar Badran, PhD
Medical University of South Carolina, Charleston, SC
3:05-3:10pm EST Break
3:10-3:45pm EST Combining Neuromodulation and Regenerative Rehabilitation
Jonathan Wolpaw, MD
National Center for Adaptive Neurotechnologies, Albany, NY
3:45-3:55pm EST AR3T and NC NM4R Joint Pilot Grant Awardee
Koyal Garg, PhD
St. Louis University, St. Louis, MO
3:55-4:00pm EST Break
4:00-4:50pm EST Idea Pitches and Discussion
Workshop Attendees
4:50-5:00pm EST Closing Remarks

Contact with questions.