Below is a list of multidisciplinary Core competencies that support the breadth of Regenerative Rehabilitation research. Select one to learn about AR3T’s researchers with expertise in that area. Learn more about collaborative projects, consultations and sabbatical experiences that are available through the AR3T resource center here.
Core 3: Rehabilitation & Mechanosensitive Biomarkers
Central and peripheral nervous system researchers:
- George Laboratory: Paul George’s laboratory focuses on applying biomaterials to interact with the nervous system in new ways and determining important mechanisms of neural recovery. Electrical stimulation is being studied as a potential mechanism for manipulating stem cells in vivo. Through the use of engineered biomaterials, he hopes to create the optimal environment for neural recovery.
- Watkins Laboratory: Dr. Simon Watkins is the founder and director of the Center for Biologic Imaging at the University of Pittsburgh and a member of the Pittsburgh Cancer Institute.
- Wyss-Coray Laboratory: Dr. Tony Wyss-Coray’s laboratory studies the role of immune and injury responses in neurodegeneration and Alzheimer’s disease. His laboratory seeks to understand how immune responses and injury pathways may modulate neurodegeneration and age-related changes in the brain. Dr. Wyss-Coray and his team study these pathways in vivo and in cell culture using a number of genetic and proteomic tools. They have been particularly interested in the fibrogenic pathways as major regulators of biological processes, and they are developing genetic/pharmacological agents to manipulate these pathways.
- Jones Laboratory: Dr. Theresa Jones studies plasticity of neural structure and synaptic connectivity in adult animals following brain damage and during skill learning. Her research in rodent stroke models indicates that this neural remodeling response is extremely sensitive to behavioral changes, including compensatory behaviors that animals develop spontaneously and those induced by motor rehabilitative training.