The AR3T Pilot Funding Program supports researchers in the development of innovative, interdisciplinary Regenerative Rehabilitation research projects.
AR3T is not accepting new pilot grant proposals at this time.
Overview: Stem cells interpret mechanical forces in a broad spectrum of ways that can affect their behavior and, ultimately, their ability to drive tissue regeneration. AR3T is looking to support researchers who propose interdisciplinary approaches combining regenerative medicine with mechanical stimulation, with the aim of optimizing outcomes.
The Regenerative Rehabilitation research community is benefiting from the development of novel lines of research that incorporate methods utilizing electrical or mechanical stimulation of stem cells, applied biophysics and/or tissue engineering approaches, and assessing stem cell behavior and/or functional outcomes.
A proposed project must include both a regenerative medicine/stem cell biology component as well as a rehabilitative/mechanotransductive component. Contact firstname.lastname@example.org if you would be interested in forming a collaboration with an AR3T researcher on a proposal.
Eligible Individuals: The AR3T pilot funding program is open to junior investigators and mid-level career faculty. The Principal Investigator (PI) should have a doctoral degree in a relevant field and be employed at an nonprofit institution within the United States. The goal is to fund researchers who are interested in beginning a career in Regenerative Rehabilitation research or who would like to start a new line of research in this area.
Examples of funded pilot projects include:
- Paul George (Stanford): Conductive nerve guides to augment cell therapy
- Liang-Ching Tsai (Georgia State University): Joint loading modulation on post-injury knee OA
- Janet Zoldan (University of Texas): Promoting neurovascularization following stroke
- Sunil Gandhi (University of California, Irvine): Enhancing motor retraining using stem cell therapy
- Spencer Szczesny (Pennsylvania State University): Stem cell mechanotransduction with tendon fatigue
- David Mooney (Harvard University): Robotic actuator for in vivo muscle stimulation
- Michel Modo (University of Pittsburgh): Neuro-biological effects of rehabilitation on neural stem cell transplantation after stroke
- Sarah Heilshorn (Stanford): Protein-engineered nerve guidance conduits for peripheral nerve injury recovery and rehabilitation
- Jarrod Call (UGA) and Sarah Greising (USAISR): Early interventions for orthopedic combat casualties
- Joseph Roche (Wayne State): Novel rehabilitative interventions for muscle loss
- Ngan Huang (PAVIR): Nano-aligned scaffold conjugated with insulin-like growth factor-1 mRNA for treatment of volumetric muscle loss
- Riccardo Gottardi (University of Pittsburgh): R-CaRe-Rehabilitation for cartilage regeneration
- David Mack (University of Washington): Electromechanical maturation of iPSC-derived myotubes in vitro