Pilot Grants

Pilot Grants2021-02-02T18:17:34+00:00

The AR3T Pilot Funding Program supports researchers in the development of innovative, interdisciplinary Regenerative Rehabilitation research projects. 

Congratulations to AR3T’s newest pilot grant recipients!

Joel Boerckel, PhD (University of Pennsylvania) and Nick Willett, PhD (Emory University) “The Role of YAP/TAZ Mechanotransduction in Regenerative Rehabilitation for Bone Defect Repair”

Jennifer Puetzer, PhD (Virginia Commonwealth University)  "Driving Zonal Stem Cell Differentiation with Developmental Mechanical Cues for Ligament-to-Bone Enthesis Regeneration"

Amrita Sahu, PhD (University of Pittsburgh) and Allison Bean, MD, PhD (University of Pittsburgh)  "Extracellular Vesicles: a Novel Acellular Regenerative Therapy for Rehabilitation of Aging Muscle"

AR3T is not accepting new pilot grant proposals at this time. 

Overview: Stem cells interpret mechanical forces in a broad spectrum of ways that can affect their behavior and, ultimately, their ability to drive tissue regeneration. AR3T is looking to support researchers who propose interdisciplinary approaches combining regenerative medicine with mechanical stimulation, with the aim of optimizing outcomes.

The Regenerative Rehabilitation research community will benefit from the development of novel lines of research that incorporate methods utilizing mechanical stimulation of stem cells and/or tissue engineering approaches, and assessing stem cell behavior and/or functional outcomes.

A proposed project must include both a regenerative medicine component as well as a rehabilitative/mechanotransductive component. We encourage you to consider collaborating with one of AR3T's researchers. Contact ar3t@pitt.edu if you would be interested in forming a collaboration on a proposal.

Eligible Individuals: The AR3T pilot funding program is open to junior investigators and mid-level career faculty. The Principal Investigator (PI) should have a doctoral degree in a relevant field and be employed at an institution within the United States. The goal is to fund researchers who are interested in beginning a career in Regenerative Rehabilitation research or who would like to start a new line of research in this area.

Examples of funded pilot projects include:

  • Paul George (Stanford): Conductive nerve guides to augment cell therapy
  • Liang-Ching Tsai (Georgia State University): Joint loading modulation on post-injury knee OA
  • Janet Zoldan (University of Texas): Promoting neurovascularization following stroke
  • Sunil Gandhi (University of California, Irvine): Enhancing motor retraining using stem cell therapy
  • Spencer Szczesny (Pennsylvania State University): Stem cell mechanotransduction with tendon fatigue
  • David Mooney (Harvard University): Robotic actuator for in vivo muscle stimulation
  • Michel Modo (University of Pittsburgh): Neuro-biological effects of rehabilitation on neural stem cell transplantation after stroke
  • Sarah Heilshorn (Stanford): Protein-engineered nerve guidance conduits for peripheral nerve injury recovery and rehabilitation
  • Jarrod Call (UGA) and Sarah Greising (USAISR): Early interventions for orthopedic combat casualties
  • Joseph Roche (Wayne State): Novel rehabilitative interventions for muscle loss
  • Ngan Huang (PAVIR): Nano-aligned scaffold conjugated with insulin-like growth factor-1 mRNA for treatment of volumetric muscle loss
  • Riccardo Gottardi (University of Pittsburgh): R-CaRe-Rehabilitation for cartilage regeneration
  • David Mack (University of Washington): Electromechanical maturation of iPSC-derived myotubes in vitro

Additional Information

  • We are not currently accepting pilot grant proposals. Subscribe to the AR3T newsletter in order to receive the latest news on research and grant opportunities for Regenerative Rehabilitation researchers.
  • For questions and/or assistance with proposal development, contact us at ar3t@pitt.edu.