The Nakayama Laboratory works on developing engineered and regenerative therapies to treat cardiovascular and musculoskeletal injuries and disease using spatially patterned biomaterials and rehabilitation exercise. Dr. Nakayama received her Ph.D. from the Department of Biomedical Engineering at the University of California, Davis. During her doctoral training, she worked towards developing regenerative therapies for congenital kidney diseases using decellularized extracellular matrices and stem cell-derived renal precursors.
Dr. Nakayama completed her postdoctoral training at the Stanford University School of Medicine in the Department of Cardiothoracic Surgery. During her time at Stanford, her research focused on building iPSC-derived small diameter vascular grafts and myocardial tissues and enhancing angiogenesis in ischemic and severely damaged limbs through the manipulation of the spatial and mechanical properties of biomaterials.
Dr. Nakayama joined the faculty at Oregon Health & Science University (OHSU) in the Department of Biomedical Engineering as an Assistant Professor in January of 2020. The overarching scientific mission of the Nakayama lab is to develop therapeutic treatments for traumatic musculoskeletal injuries using regenerative bioengineering strategies. The goals of her research program are to elucidate novel biomechanical pathways that are involved in directing cell phenotype, differentiation, and function. Specifically, the group aims to modulate extracellular environments using patterned biomaterials with nano-scale features and rehabilitation exercise to stimulate the musculoskeletal regenerative niche.