Publications and Resources

Publications and Resources2023-06-27T18:51:04+00:00

Click each heading to find a list of publications and resources.

  1. Clinical Rationale and Rehabilitation Guidelines for Post Biologic Therapy Physical Medicine Rehabilitation Clinics of North America, 2023
  2. The Role of Physical Exercise and Rehabilitative Implications in the Process of Nerve Repair in Peripheral Neuropathies: A Systematic Review Diagnostics, 2023
  3. Precision Rehabilitation: Optimizing Function, Adding Value to Health Care Archives of Physical Medicine and Rehabilitation, 2022
  4.  Novel Strategies for Spinal Cord Regeneration International Journal of Molecular Sciences, 2022
  5. The role of electrical stimulation for rehabilitation and regeneration after spinal cord injury Journal of Orthopaedics and Traumatology, 2022
  6.  Regenerative Rehabilitation and Stem Cell Therapy Targeting Chronic Spinal Cord Injury: A Review of Preclinical Studies Cells, 2022
  7. Recent and Future Strategies of Mechanotherapy for Tissue Regenerative Rehabilitation ACS Biomaterials, 2022
  8. Reverse Dynamisation: A Modern Perspective on Stephan Perren’s Strain Theory European Cells & Materials, 2021
  9. Traumatic Injury to the Developing Brain: Emerging Relationship to Early Life Stress Frontiers of Neurology, 2021
  10. Progressing the field of Regenerative Rehabilitation through novel interdisciplinary interaction Nature, 2020
  11. Regenerative rehabilitation of catastrophic extremity injury in military conflicts and a review of recent developmental efforts Connective Tissue Efforts, 2020
  12. Taking the Next Steps in Regenerative Rehabilitation: Establishment of a New Interdisciplinary Field Archives of  Physical Medicine and Rehabilitation, 2020
  13. Musculoskeletal Regeneration, Rehabilitation, and Plasticity Following Traumatic Injury, International Journal of Sports Medicine, 2020
  14. Regenerative Rehabilitation for Stroke Recovery by Including Synergistic Effects of Cell Therapy and Neurorehabilitation on Motor Function: A Narrative Review of Pre-Clinical Studies International Journal of Molecular Science, 2020
  15. Short Review on Advancement of Ostheoarthritis Treatment with Cell Therapy Journal of Regenerative Biology and Medicine, 2020
  16. Past, Current and Future Interventional Orthobiologics Techniques and How they Relate to Regenerative Rehabilitation: A Clinical Commentary International Journal of Sports Physical Therapy, 2020
  17. Use of Adipose‐Derived Orthobiologics for Musculoskeletal Injuries: A Narrative Review PM&R, 2019
  18. Bioscaffold-Induced Brain Tissue Regeneration Frontiers in Neuroscience, 2019
  19. Potential Role of Physical Therapy in the Field of Genetic and Cellular Rehabilitation: A Review of Literature International Journal of Health Sciences and Research, 2019
  20.  A Forward Move: Interfacing Biotechnology and Physical Therapy In and Out of the Classroom Physical Therapy, 2019
  21.  Stem Cell Therapy for Knee Osteoarthritis: A Narrative Review of a Rapidly Evolving Treatment with Implications for Physical Therapy Management Physical Therapy Reviews, 2019
  22.  Regenerative Medicine Curriculum for Next-generation Physicians npj Regenerative Medicine, 2019
  23.  Recreating Embryonic Conditions at Break Sites can Help Bones Heal Faster Science Daily, 2019
  24.  Regenerative Rehabilitation of the Musculoskeletal System Ovid, 2019
  25.  The Convergence of Regenerative Medicine and Rehabilitation: Federal Perspectives npj Regenerative Medicine, 2018
  26.  The Regenerative Rehabilitation Collection: A Forum for an Emerging Field npj Regenerative Medicine, 2018
  27.  Rehabilitation Following Regenerative Medicine Treatment for Knee Osteoarthritis-Current Concept Review Journal of Clinical Orthopaedics and Trauma, 2018
  28. Regenerative Rehabilitation: The Role of Mechanotransduction in Orthopaedic Regenerative Medicine  Journal of Orthopaedic Research, 2018
  29.  Regenerative Rehabilitation: Applied Biophysics Meets Stem Cell Therapeutics Cell Stem Cell, 2018
  30.  Regenerative Rehabilitation: Combining Stem Cell Therapies and Activity Dependent Simulation Pediatric Physical Therapy, 2017
  31. Cellular Rehab: Physical Therapy and Exercise are Critical to the Success of Cell Therapies Approaching the Clinic. The Scientist, 2015
  32. Regenerative Rehabilitation: A New Future? American Journal of Physical Medicine & Rehabilitation, 2014
  33. Opportunities for Regenerative Rehabilitation and Advanced Technologies in Physical Therapy: Perspective From Academia. Physical Therapy, 2016
  34. The Role of PTs in Regenerative Medicine PT in Motion, 2016
  35. The Role of Physiatry in Regenerative Medicine: The Past, The Present, and Future Challenges PM&R, 2015
  36. Regenerative Rehabilitation and Genomics: Frontiers in Clinical Practice. Physical Therapy, 2016
  37. Neural Stem Cell Therapy and Rehabilitation in the Central Nervous System: Emerging Partnerships Physical Therapy, 2016
  38. Developmental Biology and Regenerative Medicine: Addressing the Vexing Problem of Persistent Muscle Atrophy in the Chronically Torn Human Rotator Cuff Physical Therapy, 2016
  39. Regenerative Principles Enrich Cardiac Rehabilitation Practice American Journal of Physical Medicine & Rehabilitation, 2015
  40. Emergent Themes from Second Annual Symposium on Regenerative Rehabilitation, Pittsburgh, Pennsylvania  Journal of Rehabilitation Research and Development, 2014
  41. Toward a Convergence of Regenerative Medicine, Rehabilitation, and Neuroprosthetics Journal of Neurotrauma, 2011
  42. The Emerging Relationships between Regenerative Medicine and Physical Therapeutics  Journal of Rehabilitation Research and Development, 2013
  43. Regenerative Rehabilitation: A Call To Action Journal of Rehabilitation Research and Development, 2010
  44. Youtube video collection on Regenerative Rehabilitation
  1. NEW! Neuromuscular electrical stimulation enhances the ability of serum extracellular vesicles to regenerate aged skeletal muscle after injury Experimental Gerontology, 2023
  2. Effects of Adjunct Antifibrotic Treatment within a Regenerative Rehabilitation Paradigm for Volumetric Muscle Loss International Journal of Molecular Sciences, 2023
  3. Rehabilitative Training Enhances Therapeutic Effect of Human-iPSC-Derived Neural Stem/Progenitor Cells Transplantation in Chronic Spinal Cord Injury Stem Cells Translational Medicine, 2023
  4.  Regenerative rehabilitation with conductive biomaterials for spinal cord injury Acta Biomaterialia, 2022
  5. Recent and Future Strategies of Mechanotherapy for Tissue Regenerative Rehabilitation ACS Biomaterials Science & Engineering, 2022
  6. Comparative Effects of Basic Fibroblast Growth Factor Delivery or Voluntary Exercise on Muscle Regeneration after Volumetric Muscle Loss Bioengineering, 2022
  7. Sensory Restoration by Epidural Stimulation of the Lateral Spinal Cord in Upper-Limb Amputees eLife, 2021
  8. Cross-talk with skeletal muscle and its nexus with regenerative rehabilitation Connective Tissue Research, 2020
  9. Combating osteoporosis and obesity with exercise: leveraging cell mechanosensitivity Nature Reviews Endocrinology, 2020
  10. Effects of extracellular matrix viscoelasticity on cellular behaviour Nature, 2020
  11. Regenerative rehabilitation: exploring the synergistic effects of rehabilitation and implantation of a bio-functional scaffold in enhancing nerve regeneration Biomaterials Science, 2020
  12. Advances in electrical and magnetic stimulation on nerve regeneration Regenerative Medicine, 2020
  13. Extracellular matrix compression temporally regulates microvascular angiogenesis Applied Sciences and Engineering, 2020
  14. Magnetic biomaterials and nano-instructive tools as mediators of tendon mechanotransduction Nanoscale Advances, 2020
  15. Transplantation of insulin-like growth factor-1 laden scaffolds combined with exercise promotes neuroregeneration and angiogenesis in a preclinical muscle injury model Biomaterials Science, 2020
  16. Effects of extracellular matrix viscoelasticity on cellular behaviour Nature, 2020
  17. Mechanical Regulation of Microvascular Angiogenesis bioRxiv, 2020
  18. Effects of osteogenic ambulatory mechanical stimulation on early stages of BMP-2 mediated bone repair bioRxiv, 2020
  19. Wireless sensor enables longitudinal monitoring of regenerative niche mechanics during rehabilitation that enhance bone repair Bone, 2020
  20. Wireless Sensor Enables Longitudinal Monitoring of Regenerative Nice Mechanics During Rehabilitation that Enhance Bone Repair Bone, 2020
  21. Muscular Dystrophy and Rehabilitation Interventions with regenerative Treatment Current Physical Medicine and Rehabilitation Reports, 2020
  22. Single-Session Cortical Electrical Stimulation Enhances the Efficacy of Rehabilitative Motor Training After Spinal Cord Injury in Rats Experimental Neurology, 2020
  23. Biomedical Applications of Electrical Stimulation Cellular and Molecular Life Sciences, 2020
  24. American Society for Bone and Mineral Research‐Orthopaedic Research Society Joint Task Force Report on Cell‐Based Therapies Journal of Orthopaedic Research, 2020
  25. Shear Stress Promotes Arterial Endothelium-Oriented Differentiation of Mouse-Induced Pluripotent Stem Cells Stem Cells International, 2019
  26. Locomotor Training with Adjuvant Testosterone Preserves Cancellous Bone and Promotes Muscle Plasticity in Male Rats After Severe Spinal Cord Injury Journal of Neuroscience Research, 2019
  27. Rehabilitation following regenerative medicine treatment for knee osteoarthritis-current concept review Journal of Clinical Orthopaedics and Trauma, 2019
  28. Regenerative rehabilitation: exploring the synergistic effects of rehabilitation and implantation of a bio-functional scaffold in enhancing nerve regeneration Royal Society of Chemistry, 2019
  29. Regenerative rehabilitation: The role of mechanotransduction in orthopaedic regenerative medicine Journal of Orthopaedic Research, 2019
  30. Multi-Disciplinary Approaches for Cell-Based Cartilage Regeneration Orthopedic Research Society, 2019
  31. Massage increases satellite cell number independent of the age‐associated alterations in sarcolemma permeability Physiological Reports, 2019
  32. Myoblast maturity on aligned microfiber bundles at the onset of strain application impacts myogenic outcomes Acta Biomaterialia, 2019
  33. The Role of Reactive Oxygen Soecies in In Vitro Cardiac Maturation Trends in Molecular Medicine, 2019
  34. Updates in Multi-Disciplinary Approaches for Stem-Cell Based Cartilage Orthopedic Research Society, 2019
  35. Analysis and Modeling of Rat Gait Biomechanical Deficits in Response to Volumetric Muscle Loss Injury Frontiers in Bioengineering and Biotechnology, 2019
  36. Dynamic Compressive Loading Improves Cartilage Repair in an In Vitro Model of Microfracture: Comparison of 2 Mechanical Loading Regimens on Simulated Microfracture Based on Fibrin Gel Scaffolds Encapsulating Connective Tissue Progenitor Cells The American Journal of Sports Medicine, 2019
  37. Review of the Current Knowledge on the Role of Stem Cell Transplantation in Neurorehabilitation BioMed Research International, 2019
  38. Multi‐Disciplinary Approaches for Cell‐Based Cartilage Regeneration Journal of Orthopaedic Research, 2019
  39. Continuous Low-Intensity Ultrasound Promotes Native-To-Native Cartilage Integration Tissue Engineering Part A, 2019
  40. 6.5 Scientific Background of Physical and Rehabilitation Medicine: Rehabilitation Sciences The Journal of The International Society of Physical and Rehabilitation Medicine, 2019
  41. The Future of Animal Modeling for Post-Stroke Tissue Repair Stroke, 2018
  42.  PGC-1α Overexpression Partially Rescues Impaired Oxidative and Contractile Pathophysiology Following Volumetric Muscle Loss Injury Scientific Reports, 2018
  43. Production of Elastin-Like Protein Hydrogels for Encapsulation and Immunostaining of Cells in 3D Journal of Visualized Experiments, 2018
  44. Rehabilitative Exercise and Spatially Patterned Nanofibrillar Scaffolds Enhance Vascularization and Innervation Following Volumetric Muscle Loss npj Regenerative Medicine, 2018
  45. Aligned Nanofibrillar Scaffolds for Controlled Delivery of Modified mRNA Tissue Engineering Part A, 2019
  46. Engineering Biomimetic Materials for Skeletal Muscle Repair and Regeneration Advanced Healthcare Materials, 2019
  47. Extracellular Matrix Remodelling Induced by Alternating Electrical and Mechanical Stimulations Increases the Contraction of Engineered Skeletal Muscle Tissues Scientific Reports, 2019
  48. Translation of Remote Control Regenerative Technologies for Bone Repair npj Regenerative Medicine, 2018
  49. Rehabilitative Exercise and Spatially Patterned Nanofibrillar Scaffolds Enhance Vascularization and Innervation Following Volumetric Muscle Loss npj Regenerative Medicine, 2018
  50. Effectiveness of Mesenchymal Stem Cells for Treating Patients with Knee Osteoarthritis: A Meta-Analysis Toward the Establishment of Effective Regenerative Rehabilitation npj Regenerative Medicine, 2018
  51. Environmental Influences on Stem Cell Behavior Stem Cells International, 2018
  52. Early Rehabilitation for Volumetric Muscle Loss Injury Augments Regenerative Aspects of Muscle Strength and Oxidative Capacity  BMC Musculoskeletal Disorders, 2018
  53. Bioengineered Constructs Combined with Exercise Enhance Stem Cell-Mediated Treatment of Volumetric Muscle Loss Nature Communications, 2017
  54. Biological Effects of Dosing Aerobic Exercise and Neuromuscular Electrical Stimulation in Rats Scientific Reports, 2017
  55. Targeted Rehabilitation After Extracellular Matrix Scaffold Transplantation for the Treatment of Volumetric Muscle Loss American Journal of Physical Medicine and Rehabilitation, 2014
  56. Neuromuscular Electrical Stimulation as a Method to Maximize the Beneficial Effects of Muscle Stem Cells Transplanted into Dystrophic Skeletal Muscle  PLOS ONE, 2013
  57. The Synergistic Effect of Treadmill Running on Stem-Cell Transplantation to Heal Injured Skeletal Muscle  Tissue Engineering Part A, 2010
  58. Interactive Effects of Cell Therapy and Rehabilitation Realize the Full Potential of Neurogenesis in Brain Injury Model  Neuroscience Letters, 2013
  59. Gene Therapy for Inherited Muscle Diseases: Where Genetics Meets Rehabilitation Medicine  American Journal of Physical Medicine and Rehabilitation, 2015
  60. Regenerative and Rehabilitative Medicine: A Necessary Synergy for Functional Recovery from Volumetric Muscle Loss Injury Cells Tissues Organs, 2015

AR3T has a Cellular Therapeutics/Tissue Engineering Core that has expertise and training in this area, with researchers who are available for consultations.

  1. NEW! Cartilage Tissue Engineering: An Introduction Methods in Molecular Biology, 2023
  2. NEW! Bioengineered 3D Skeletal Muscle Model Reveals Complement 4b as a Cell-Autonomous Mechanism of Impaired Regeneration with Aging Advanced Materials, 2023
  3. Scalable macroporous hydrogels enhance stem cell treatment of volumetric muscle loss Biomaterials, 2022
  4. Mechanical and strain behaviour of human Achilles tendon during in vitro testing to failure European Cells & Materials, 2022
  5. Conductive and injectable hyaluronic acid/gelatin/gold nanorod hydrogels for enhanced surgical translation and bioprinting Journal of Biomedical Materials Research, Part A, 2022
  6. Therapeutic Implications of Transplanted-Cell Death Nature Biomedical Engineering, 2021
  7. Effects of extracellular matrix viscoelasticity on cellular behaviour Nature, 2020
  8.  Myoblast maturity on aligned microfiber bundles at the onset of strain application impacts myogenic outcomes Acta Biomaterialia, 2019
  9. Treatment of Volumetric Muscles Loss in Mice Using Nanofibrillar Scaffolds Enhances Vascular Organization and Integration Communications Biology, 2019
  10. Designer Stem Cells: Genome Engineering and the Next Generation of Cell-Based Therapies Journal of Orthopaedic Research, 2019
  11. A Roadmap for Promoting Endogenous in situ Tissue Restoration Using Inductive Bioscaffolds After Acute Brain Injury Brain Research Bulletin, 2019
  12. Review of the Current Knowledge on the Role of Stem Cell Transplantation in Neurorehabilitation BioMed Research International, 2019
  13. Multi‐Disciplinary Approaches for Cell‐Based Cartilage Regeneration Journal of Orthopaedic Research, 2019
  14. Stem cell therapy for knee osteoarthritis: a narrative review of a rapidly evolving treatment with implications for physical therapy management Physical Therapy Reviews, 2019
  15. Damaged muscle fibers might masquerade as hybrid fibers – a cautionary note on immunophenotyping mouse muscle with mouse monoclonal antibodies European Journal of Histochemistry, 2018
  16. In Vitro Repair of Meniscal Radial Tear With Hydrogels Seeded With Adipose Stem Cells and TGF-β3 The American Journal of Sports Medicine, 2018
  17. Engineering Biomimetic Materials for Skeletal Muscle Repair and Regeneration Advanced Healthcare Materials, 2019
  18. Aligned Nanofibrillar Scaffolds for Controlled Delivery of Modified mRNA Tissue Engineering Part A, 2019
  19. Therapeutic Effects of Combined Cell Transplantation and Locomotor Training in Rats With Brain Injury npj Regenerative Medicine, 2019
  20. Regenerative Rehabilitation of the Musculoskeletal System American Academy of Orthopedic Surgery, 2018
  21. Production of Elastin-like Protein Hydrogels for Encapsulations and Immunostaining of Cells in 3D Journal of Visual Experiments, 2018
  22. An Acellular Biologic Scaffold Promotes Skeletal Muscle Formation in Mice and Humans with Volumetric Muscle Loss Science Translational Medicine, 2014
  23. Mesenchymal Stem Cells: Identification, Phenotypic Characterization, Biological Properties and Potential for Regenerative Medicine through Biomaterial Micro-Engineering of Their Niche Methods, 2016
  24. Stem Cells and Healthy Aging Science, 2015
  25. Extracellular Matrix Bioscaffolds in Tissue Remodeling and Morphogenesis Developmental Dynamics, 2015
  26. Biologic Scaffolds for Regenerative Medicine: Mechanisms of In vivo Remodeling Annals of Biomedical Engineering, 2014
  27. Cell-Derived Matrices for Tissue Engineering and Regenerative Medicine Applications Biomaterials Science, 2015
  28. Sexual Dimorphism in Stem Cell-Based Therapies for the Musculoskeletal System Operative Techniques in Orthopaedics, 2016
  29. Cell-Derived Extracellular Matrix: Basic Characteristics and Current Applications in Orthopedic Tissue Engineering Tissue Engineering Part B: Reviews, 2016
  30. Biomaterials Control of Pluripotent Stem Cell Fate for Regenerative Therapy Progress in Materials Science, 2016
  31. Intracerebral Cell Implantation: Preparation and Characterization of Cell Suspensions Cell Transplantation, 2016
  32. Stem Cells in Skeletal Tissue Engineering: Technologies and Models  Current Stem Cell Research and Therapy, 2016
  33. Synergizing Engineering and Biology to Treat and Model Skeletal Muscle Injury and Disease Annual Review of Biomedical Engineering, 2015
  34. Youtube Video Collection on Tissue Engineering and Cellular Therapeutics

AR3T has a Mechanotransductive Core that has expertise in this area, with researchers who are available to provide consultations.

  1. NEW! Mouse Achilles tendons exhibit collagen disorganization but minimal collagen denaturation during cyclic loading to failure Journal of Biomechanics, 2023
  2. NEW! Dynamical modeling reveals RNA decay mediates the effect of matrix stiffness on aged muscle stem cell fate bioRxiv, 2023 (preprint)
  3. NEW! Age-related matrix stiffening epigenetically regulates α-Klotho expression and compromises chondrocyte integrity Nature Communications, 2023
  4. A Novel, Open Source, Low-Cost Bioreactor for Load-Controlled Cyclic Loading of Tendon Explants Journal of Biomechanical Engineering, 2o22
  5. A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues Science Advances, 2021
  6. Soft Tissue Manipulation May Attenuate Inflammation, Modulate Pain, and Improve Gait in Conscious Rodents With Induced Low Back Pain Military Medicine, 2021
  7. Mechanical stimulation of human dermal fibroblasts regulates pro-inflammatory cytokines: potential insight into soft tissue manual therapies BMC Research Notes, 2020
  8. Effects of extracellular matrix viscoelasticity on cellular behaviour Nature, 2020
  9. Engineering of human cardiac muscle electromechanically matured to an adult-like phenotype Nature Protocols, 2020
  10. Extracellular matrix compression temporally regulates microvascular angiogenesis Applied Sciences and Engineering, 2020
  11. Magnetic biomaterials and nano-instructive tools as mediators of tendon mechanotransduction Nanoscale Advances, 2020
  12. Effects of osteogenic ambulatory mechanical stimulation on early stages of BMP-2 mediated bone repair bioRxiv, 2020
  13. Wireless sensor enables longitudinal monitoring of regenerative niche mechanics during rehabilitation that enhance bone repair Bone, 2020
  14.  Regenerative rehabilitation: The role of mechanotransduction in orthopaedic regenerative medicine Journal of Orthopaedic Research, 2019
  15. Effects of Treadmill Running and Limb Immobilization on Knee Cartilage Degeneration and Locomotor Joint Kinematics in Rats Following Knee Meniscal Transection Osteoarthritis and Cartilage, 2019
  16. Real-Time Monitoring of Mechanical Cues in the Regenerative Niche Reveal Dynamic Strain Magnitudes that Enhance Bone Repair bioRxiv, 2019
  17. Soft Tissue Manipulation: A Powerful Form of Mechanotherapy Journal of Physiotherapy and Physical Rehabilitation, 2016
  18. Biomechanical Stimulus Based Strategies for Meniscus Tissue Engineering and Regeneration Tissue Engineering Part B: Reviews, 2018
  19. Enhanced Neural Stem Cell Functions in Conductive Annealed Carbon Nanofibrous Scaffolds with Electrical Stimulation Nanomedicine: Nanotechnology, Biology and Medicine, 2018
  20. A Guide for Using Mechanical Stimulation to Enhance Tissue-Engineered Articular Cartilage Properties Tissue Engineering Part B: Reviews, 2018
  21. Understanding Mechanobiology: Physical Therapists as a Force in Mechanotherapy and Musculoskeletal Regenerative Rehabilitation  Physical Therapy, 2016
  22. Mechanotransduction: Relevance to Physical Therapist Practice—Understanding Our Ability to Affect Genetic Expression Through Mechanical Forces Physical Therapy, 2016
  23. Force Transmission in Epithelial Tissues Developmental Dynamics, 2016
  24. Substrate Stiffness Controls Osteoblastic and Chondrocytic Differentiation of Mesenchymal Stem Cells without Exogenous Stimuli PLOS ONE, 2017
  25. Mechanical and Vascular Cues Synergistically Enhance Osteogenesis in Human Mesenchymal Stem Cells  Tissue Engineering Part A, 2016
  26. Asymmetrical Seeding of MSCs into Fibrin–Poly(Ester-Urethane) Scaffolds and Its Effect on Mechanically Induced Chondrogenesis Journal of Tissue Engineering and Regenerative Medicine, 2016
  27. Gene Therapy for Inherited Muscle Diseases: Where Genetics Meets Rehabilitation Medicine American Journal of Physical Medicine and Rehabilitation, 2014
  28. Youtube video collection on Mechanobiology and Mechanotransduction
  29. Cell Mechanosensitivity to Extremely Low-Magnitude Signals is Enabled by a LINCed Nucleus Stem Cells, 2015
  30. Concise Review: Plasma and Nuclear Membranes Convey Mechanical Information to Regulate Mesenchymal Stem Cell Lineage Stem Cells, 2016
  31. The Nucleus is a Conserved Mechanosensation and Mechanoresponse Organelle Cytoskeleton, 2016
  32. Bone and Skeletal Muscle: Key Players in Mechanotransduction and Potential Overlapping Mechanisms Bone, 2015

AR3T has a Biomarker Core that has expertise in this area, with researchers who are available to provide consultations.

  1. Resistance exercise differentially alters extracellular vesicle size and subpopulation characteristics in healthy men and women: an observational cohort study Physiological Genomics, 2022
  2. Neuroendocrine, inflammatory, and extracellular vesicle responses during the Navy Special Warfare Screener Selection Course Physiological Genomics, 2022
  3. Men and women display distinct extracellular vesicle biomarker signatures in response to military operational stress Journal of Applied Physiology, 2022
  4. Utility of extracellular vesicles as a potential biological indicator of physiological resilience during military operational stress Physiological Reports, 2022
  5. Exercise as a rehabilitation intervention for severe burn survivors: Benefits & barriers Burns, 2022
  6. Precision Rehabilitation: Optimizing Function, Adding Value to Health Care Archives of Physical Medicine and Rehabilitation, 2022
  7. The fidelity of genetic information transfer with aging segregates according to biological processes bioRxiv, 2022
  8. Identification of miRNA Reference Genes in Extracellular Vesicles from Adipose Derived Mesenchymal Stem Cells for Studying Osteoarthritis International Journal of Molecular Sciences, 2019
  9. ‘Longevity Protein’ Enables Muscle Regeneration In Old Mice Forbes, 2018
  10. The Development of Biomarkers for Degenerative Musculoskeletal Conditions Discovery Medicine, 2014
  11. NF-κB Signaling Pathway in Controlling Intervertebral Disk Cell Response to Inflammatory and Mechanical Stressors Physical Therapy, 2016
  12. Biomarker Development for Musculoskeletal Diseases PM&R, 2011
  13. Associations Between Serum Biomarkers and Pain and Pain-Related Function in Older Adults with Low Back Pain: A Pilot Study Journal of the American Geriatrics Society, 2014
  14. Quantification of GDF11 and Myostatin in Human Aging and Cardiovascular Disease Cell Metabolism, 2016
  15. Non-CG DNA Methylation is a Biomarker for Assessing Endodermal Differentiation Capacity in Pluripotent Stem Cells Nature Communications, 2016

Rehabilomics Research:

  1. A Rehabilomics Framework for Personalized and Translational Rehabilitation Research and Care for Individuals With Disabilities: Perspectives and Considerations for Spinal Cord Injury The Journal of Spinal Cord Medicine, 2014
  2. Rehabilomics Research: A Model for Translational Rehabilitation and Comparative Effectiveness Rehabilitation Research abstract American Journal of Physical Medicine and Rehabilitation, 2014

AR3T supports technology development for this purpose.

  1. NEW! Measuring Local Tissue Strains in Tendons via Open-Source Digital Image Correlation Journal of Visualized Experiments, 2023
  2. NEW! Anti-inflammatory therapy enables robot-actuated regeneration of aged muscle Science Robotics, 2023
  3. NEW! AutoRG: An automatized reach-to-grasp platform technology for assessing forelimb motor function, neural circuit activation, and cognition in rodents Journal of Neuroscience Methods, 2023
  4. Full-Length Dystrophin Deficiency Leads to Contractile and Calcium Transient Defects in Human Engineered Heart Tissues Journal of Tissue Engineering, 2022
  5. High-Throughput, Real-Time Monitoring of Engineered Skeletal Muscle Function Using Magnetic Sensing Journal of Tissue Engineering, 2022
  6. Skeletal Muscle Regeneration with Robotic Actuation-Mediated Clearance of Neutrophils Science Translational Medicine, 2021
  7. Wireless Sensor Enables Longitudinal Monitoring of Regenerative Nice Mechanics During Rehabilitation that Enhance Bone Repair Bone, 2020
  8. 3D Printed Biaxial Stretcher Compatible with Live Fluorescence Microscopy HardwareX, 2020
  9. Regenerative rehabilitation: exploring the synergistic effects of rehabilitation and implantation of a bio-functional scaffold in enhancing nerve regeneration Royal Society of Chemistry, 2019
  10. Development and characterization of ZnO piezoelectric thin films on polymeric substrates for tissue repair Journal of Biomedical Materials Research, 2019
  11. An In Vitro 3D Model and Computational Pipeline to Quantify the Vasculogenic Potential of iPSC-Derived Endothelial Progenitors JoVE, 2019
  12. A Short-Term Plastic Adherence Incubation of the Stromal Vascular Fraction Leads to a Predictable GMP-Compliant Cell-Product Bioimpacts, 2019
  13. Raman Spectroscopy As a Quick Tool to Assess Purity of Extracellular Vesicle Preparations and Predict Their Functionality Journal of Exracellular Vesicles, 2019
  14. Measuring Clinically Relevant Knee Motion with a Self-Calibrated Wearable Sensor Journal of Biomechanics, 2019
  15. Analysis and Modeling of Rat Gait Biomechanical Deficits in Response to Volumetric Muscle Loss Injury Frontiers in Bioengineering and Biotechnology, 2019
  16. Dynamic Compressive Loading Improves Cartilage Repair in an In Vitro Model of Microfracture: Comparison of 2 Mechanical Loading Regimens on Simulated Microfracture Based on Fibrin Gel Scaffolds Encapsulating Connective Tissue Progenitor Cells The American Journal of Sports Medicine, 2019
  17. Continuous Low-Intensity Ultrasound Promotes Native-To-Native Cartilage Integration Tissue Engineering Part A, 2019
  18. Real-Time Monitoring of Mechanical Cues in the Regenerative Niche Reveal Dynamic Strain Magnitudes that Enhance Bone Repair bioRxiv, 2019
  19. Minimally Invasive Muscle Embedding (MIME) – A Novel Experimental Technique to Facilitate Donor-Cell-Mediated Myogenesis Journal of Visualized Experiments, 2018
  20. Production of Elastin-like Protein Hydrogels for Encapsulation and Immunostaining of Cells in 3D Journal of Visualized Experiments, 2018
  21. Translation of Remote Control Regenerative Technologies for Bone Repair npj Regenerative Medicine, 2018
  22. Wearable Bioreactor Heralds Leap for Regenerative Medicine The Engineer, 2018
  23. EGaIn‐Assisted Room‐Temperature Sintering of Silver Nanoparticles for Stretchable, Inkjet‐Printed, Thin‐Film Electronics Advanced Materials, 2018
  24. Microfluidic Flow Cell Array for Controlled Cell Deposition in Engineered Musculoskeletal Tissues Tissue Engineering Part C: Methods, 2018
  25. Production of Elastin-like Protein Hydrogels for Encapsulations and Immunostaining of Cells in 3D Journal of Visualized Experiments, 2018
  26. Murine Model of Robotic Training to Evaluate Skeletal Muscle Recovery After Injury Medicine and Science in Sports and Exercise, 2017
  27. Substrate Stiffness Controls Osteoblastic and Chondrocytic Differentiation of Mesenchymal Stem Cells without Exogenous Stimuli PLOS ONE, 2017
  28. A Bird’s Eye View on the Use of Electrospun Nanofibrous Scaffolds for Bone Tissue Engineering: Current State-of-the-Are, Emerging Directions and Future Trends Nanomedicine: Nanotechnology, Biology and Medicine, 2016
  29. High Throughput Screening for Discovery of Materials That Control Stem Cell Fate Current Opinion in Solid State and Materials Science, 2016
  30. A Review of Three-Dimensional Printing in Tissue Engineering Tissue Engineering Part B: Reviews, 2016
  31. Advanced Imaging Approaches for Regenerative Medicine: Emerging Technologies for Monitoring Stem Cell Fate In Vitro and In Vivo Biotechnology Journal, 2015
  32. Electrodiagnostic Evaluation of Individuals Implanted With Extracellular Matrix for the Treatment of Volumetric Muscle Injury: Case Series Physical Therapy, 2016
  33. Youtube video collection on Regenerative Medicine research technology
  1. NEW! IL-1Ra gene transfer potentiates BMP2-mediated bone healing by redirecting osteogenesis toward endochondral ossification Molecular Therapy, 2023
  2. NEW! Aging Affects the Efficacy of Platelet-Rich Plasma Treatment for Osteoarthritis American Journal of Physical Medicine and Rehabilitation, 2023
  3. NEW! Uncovering the “riddle of femininity” in osteoarthritis: a systematic review and meta-analysis of menopausal animal models and mathematical modeling of estrogen treatment Osteoarthritis and Cartilage, 2023
  4. Orthobiologic Interventions for Muscle Injuries Physical Medicine and Rehabilitation Clinics North America, 2023
  5. Regulation of Axonal Regeneration After Mammalian Spinal Cord Injury Nature Reviews Molecular Cell Biology, 2023
  6. Efficient healing of large osseous segmental defects using optimized chemically modified messenger RNA encoding BMP-2 Science Advances, 2022
  7. Expedited gene delivery for osteochondral defect repair in a rabbit knee model: A one-year investigation Osteoarthritis and Cartilage Open, 2022
  8. Meta-analysis Integrated With Multi-omics Data Analysis to Elucidate Pathogenic Mechanisms of Age-Related Knee Osteoarthritis in Mice The Journals of Gerontology, Series A, Biological Sciences and Medical Sciences, 2022
  9. Excavating FAIR Data: the Case of the Multicenter Animal Spinal Cord Injury Study (MASCIS), Blood Pressure, and Neuro-Recovery Neuroinformatics, 2022
  10. Considerations for Small Animal Physical Rehabilitation Regenerative Rehabilitation. Physiology in Health and Disease, 2022
  11. Numerous nanoparticles as drug delivery system to control secondary immune response and promote spinal cord injury regeneration Process Biochemistry, 2022
  12. Novel Cell-Based Therapeutics for Diseases of the Heart and Skeletal Muscle Regenerative Rehabilitation. Physiology in Health and Disease, 2022
  13. Efficient Healing of Large Osseous Segmental Defects Using Optimized Chemically Modified Messenger RNA Encoding BMP-2 Science Advances, 2022
  14. A Preliminary DTI Tractography Study of Developmental Neuroplasticity 5-15 Years After Early Childhood Traumatic Brain Injury Frontiers in Neurology, 2021
  15. Developmental Alterations in Cortical Organization and Socialization in Adolescents Who Sustained a Traumatic Brain Injury in Early Childhood Journal of Neurotrauma, 2021
  16. Excavating FAIR Data: the Case of the Multicenter Animal Spinal Cord Injury Study (MASCIS), Blood Pressure, and Neuro-Recovery Neuroinformatics, 2021
  17. Pre-Clinical Common Data Elements for Traumatic Brain Injury Research: Progress and Use Cases Journal of Neurotrauma, 2021
  18. Neutrophil-Specific Deletion of Syk Results in Recruitment-Independent Stabilization of the Barrier and a Long-Term Improvement in Cognitive Function After Traumatic Injury to the Developing Brain Neurobiology of Disease, 2021
  19. Oral Rehabilitation of Patients Sustaining Orofacial Injuries: The UPenn Initiative Advances in Dental Research, 2020
  20. Pre-Clinical Cell Therapeutic Approaches for Repair of Volumetric Muscle Loss Bioengineering, 2020
  21. Cortical Transplantation of Brain‐Mimetic Glycosaminoglycan Scaffolds and Neural Progenitor Cells Promotes Vascular Regeneration and Functional Recovery after Ischemic Stroke in Mice Advanced Healthcare Materials, 2020
  22. Rehabilitation Following Regenerative Medicine Treatment for Knee Osteoarthritis-Current Concept Review Journal of Clinical Orthopaedics and Trauma, 2019
  23. Should Platelet-Rich Plasma or Stem Cell Therapy Be Used to Treat Osteoarthritis? Rheumatic Disease Clinics, 2019
  24. Designer Stem Cells: Genome Engineering and the Next Generation of Cell-Based Therapies Journal of Orthopaedic Research, 2019
  25. A Roadmap for Promoting Endogenous in situ Tissue Restoration Using Inductive Bioscaffolds After Acute Brain Injury Brain Research Bulletin, 2019
  26. New Biotechnologies for Musculoskeletal Injuries The Surgeon, 2019
  27. Regenerative medicine curriculum for next-generation physicians npj Regenerative Medicine, 2019
  28. Minimally Invasive Muscle Embedding (MIME), Facilitates the Development of Functional Muscle Fibers of Human Cadaveric Origin, in Host Mice The FASEB Journal, 2019
  29. The Oriobiologic Institute 9th Annual PRP & Regenerative Medicine Symposium (TOBI 2018): Compendium of Abstracts Biologic Orthopedic Journal, 2019
  30. Minimally Invasive Muscle Embedding (MIME) – A Novel Experimental Technique to Facilitate Donor-Cell-Mediated Myogenesis  Journal of Visualized Experiments, 2017
  31. Cytokine Networks in Immune-Mediated Muscle Regeneration Journal of Immunology and Regenerative Medicine, 2018
  32.  Concise Review: Musculoskeletal Stem Cells to Treat Age-Related Osteoporosis Stem Cells Translational Medicine, 2017
  33. Mesenchymal Stem Cells: Identification, Phenotypic Characterization, Biological Properties and Potential for Regenerative Medicine through Biomaterial Micro-Engineering of Their Niche Methods, 2016
  34. Youtube Video Collection on the Topic of Regenerative Medicine
  35. Regenerative Medicine and Regenerative Rehabilitation Podcast collection
    1. Dr. Fabrisia Ambrosio -Regenerative Rehabilitation #97
    2. Dr. Tom Rando -muscle stem cell biology #111
    3. Dr. Steve Wolf  -Regenerative Rehabilitation and educating clinicians #112
    4. Dr. George Christ -musculoskeletal tissue engineering #115
    5. Dr. Michel Modo -stem cell therapy, neuroimaging and stroke #117
    6. Dr. Ravi Bellamkonda -nerve gap repair #121
    7. Dr. Jonathan Cheetham -TE for larynx, nasopharynx and trachea #124
    8. Dr. Linda Noble- Haeusslein -CNS injuries #129
    9. Dr. David Borton -spinal injuries and Regenerative Rehabilitation #133
    10. Patrick Cantini -muscle tissue engineering study #141
    11. Dr. Stephen Badylak –npj Regenerative Medicine #154
    12. Dr. Michael Boninger -Regenerative Rehabilitation #155
    13. Dr. Elisabeth Barton -skeletal muscle repair #158
    14. Dr. Rocky Tuan -musculoskeletal disorders #166
    15. Drs. Lorenzo Soletti and Bryan Brown -peripheral nerve repair #175
    16. Dr. Antonio D’Amore -artificial heart valves and cardiac patches #178
    17. Dr. Fatima Syed-Picard -craniofacial tissue engineering #179
    18. Dr. Stephen Badylak –Journal of Immunology and Regenerative Medicine #182
  1. American Regenerative Rehabilitation and GenomicsAcademy of Physical Medicine and Rehabilitation (AAPM&R)
  2. American Physical Therapy Association (APTA)
  3. International Society for Stem Cell Research
  4. McGowan Institute for Regenerative Medicine
  5. Medical Rehabilitation Research Resource Network (MR3)
  6. RegenerativeMedicine.net
  7. RegMedNet: At RegMedNet we truly believe that regenerative medicine is going to revolutionize modern healthcare. The field comprises a multidisciplinary mix of experts, from regulators to manufacturers to researchers: RegMedNet is a networking site that unites all members of the diverse regenerative medicine community, enabling them to share the latest news, inspiration and insights, and connect and collaborate in order to help this exciting field move forward at an even faster rate.
  8. Stem Cell Research and Technology Resource Center at the University of Colorado at Boulder