Publications and Resources

Publications and Resources2019-09-17T22:09:16+00:00

Click each heading to find a list of publications and resources.

  1. NEW! Recreating Embryonic Conditions at Break Sites can Help Bones Heal Faster Science Daily, 2019
  2. NEW! Regenerative Rehabilitation of the Musculoskeletal System Ovid, 2019
  3.  The Convergence of Regenerative Medicine and Rehabilitation: Federal Perspectives npj Regenerative Medicine, 2018
  4.  The Regenerative Rehabilitation Collection: A Forum for an Emerging Field npj Regenerative Medicine, 2018
  5.  Rehabilitation Following Regenerative Medicine Treatment for Knee Osteoarthritis-Current Concept Review Journal of Clinical Orthopaedics and Trauma, 2018
  6. Regenerative Rehabilitation: The Role of Mechanotransduction in Orthopaedic Regenerative Medicine  Journal of Orthopaedic Research, 2018
  7.  Regenerative Rehabilitation: Applied Biophysics Meets Stem Cell Therapeutics Cell Stem Cell, 2018
  8.  Regenerative Rehabilitation: Combining Stem Cell Therapies and Activity Dependent Simulation Pediatric Physical Therapy, 2017
  9. Cellular Rehab: Physical Therapy and Exercise are Critical to the Success of Cell Therapies Approaching the Clinic. The Scientist, 2015
  10. Regenerative Rehabilitation: A New Future? American Journal of Physical Medicine & Rehabilitation, 2014
  11. Opportunities for Regenerative Rehabilitation and Advanced Technologies in Physical Therapy: Perspective From Academia. Physical Therapy, 2016
  12. The Role of PTs in Regenerative Medicine PT in Motion, 2016
  13. The Role of Physiatry in Regenerative Medicine: The Past, The Present, and Future Challenges PM&R, 2015
  14. Regenerative Rehabilitation and Genomics: Frontiers in Clinical Practice. Physical Therapy, 2016
  15. Neural Stem Cell Therapy and Rehabilitation in the Central Nervous System: Emerging Partnerships Physical Therapy, 2016
  16. Developmental Biology and Regenerative Medicine: Addressing the Vexing Problem of Persistent Muscle Atrophy in the Chronically Torn Human Rotator Cuff Physical Therapy, 2016
  17. Regenerative Principles Enrich Cardiac Rehabilitation Practice American Journal of Physical Medicine & Rehabilitation, 2015
  18. Emergent Themes from Second Annual Symposium on Regenerative Rehabilitation, Pittsburgh, Pennsylvania  Journal of Rehabilitation Research and Development, 2014
  19. Toward a Convergence of Regenerative Medicine, Rehabilitation, and Neuroprosthetics Journal of Neurotrauma, 2011
  20. The Emerging Relationships between Regenerative Medicine and Physical Therapeutics  Journal of Rehabilitation Research and Development, 2013
  21. Regenerative Rehabilitation: A Call To Action Journal of Rehabilitation Research and Development, 2010
  22. Youtube video collection on Regenerative Rehabilitation
  1. NEW! The Future of Animal Modeling for Post-Stroke Tissue Repair Stroke, 2018
  2. NEW! PGC-1α Overexpression Partially Rescues Impaired Oxidative and Contractile Pathophysiology Following Volumetric Muscle Loss Injury Scientific Reports, 2018
  3. NEW! Production of Elastin-Like Protein Hydrogels for Encapsulation and Immunostaining of Cells in 3D Journal of Visualized Experiments, 2018
  4. NEW! Rehabilitative Exercise and Spatially Patterned Nanofibrillar Scaffolds Enhance Vascularization and Innervation Following Volumetric Muscle Loss npj Regenerative Medicine, 2018
  5. NEW! Aligned Nanofibrillar Scaffolds for Controlled Delivery of Modified mRNA Tissue Engineering Part A, 2019
  6. NEW! Engineering Biomimetic Materials for Skeletal Muscle Repair and Regeneration Advanced Healthcare Materials, 2019
  7. NEW! Extracellular Matrix Remodelling Induced by Alternating Electrical and Mechanical Stimulations Increases the Contraction of Engineered Skeletal Muscle Tissues Scientific Reports, 2019
  8. Translation of Remote Control Regenerative Technologies for Bone Repair npj Regenerative Medicine, 2018
  9. Rehabilitative Exercise and Spatially Patterned Nanofibrillar Scaffolds Enhance Vascularization and Innervation Following Volumetric Muscle Loss npj Regenerative Medicine, 2018
  10. Effectiveness of Mesenchymal Stem Cells for Treating Patients with Knee Osteoarthritis: A Meta-Analysis Toward the Establishment of Effective Regenerative Rehabilitation npj Regenerative Medicine, 2018
  11. Environmental Influences on Stem Cell Behavior Stem Cells International, 2018
  12. Early Rehabilitation for Volumetric Muscle Loss Injury Augments Regenerative Aspects of Muscle Strength and Oxidative Capacity  BMC Musculoskeletal Disorders, 2018
  13. Bioengineered Constructs Combined with Exercise Enhance Stem Cell-Mediated Treatment of Volumetric Muscle Loss Nature Communications, 2017
  14. Biological Effects of Dosing Aerobic Exercise and Neuromuscular Electrical Stimulation in Rats Scientific Reports, 2017
  15. Targeted Rehabilitation After Extracellular Matrix Scaffold Transplantation for the Treatment of Volumetric Muscle Loss American Journal of Physical Medicine and Rehabilitation, 2014
  16. Neuromuscular Electrical Stimulation as a Method to Maximize the Beneficial Effects of Muscle Stem Cells Transplanted into Dystrophic Skeletal Muscle  PLOS ONE, 2013
  17. The Synergistic Effect of Treadmill Running on Stem-Cell Transplantation to Heal Injured Skeletal Muscle  Tissue Engineering Part A, 2010
  18. Interactive Effects of Cell Therapy and Rehabilitation Realize the Full Potential of Neurogenesis in Brain Injury Model  Neuroscience Letters, 2013
  19. Gene Therapy for Inherited Muscle Diseases: Where Genetics Meets Rehabilitation Medicine  American Journal of Physical Medicine and Rehabilitation, 2015
  20. Regenerative and Rehabilitative Medicine: A Necessary Synergy for Functional Recovery from Volumetric Muscle Loss Injury Cells Tissues Organs, 2015

AR3T has a Cellular Therapeutics/Tissue Engineering Core that has expertise and training in this area, with researchers who are available for consultations.

  1. NEW! Damaged muscle fibers might masquerade as hybrid fibers – a cautionary note on immunophenotyping mouse muscle with mouse monoclonal antibodies European Journal of Histochemistry, 2018
  2. NEW! In Vitro Repair of Meniscal Radial Tear With Hydrogels Seeded With Adipose Stem Cells and TGF-β3 The American Journal of Sports Medicine, 2018
  3. NEW! Engineering Biomimetic Materials for Skeletal Muscle Repair and Regeneration Advanced Healthcare Materials, 2019
  4. NEW! Aligned Nanofibrillar Scaffolds for Controlled Delivery of Modified mRNA Tissue Engineering Part A, 2019
  5. Regenerative Rehabilitation of the Musculoskeletal System American Academy of Orthopedic Surgery, 2018
  6. Production of Elastin-like Protein Hydrogels for Encapsulations and Immunostaining of Cells in 3D Journal of Visual Experiments, 2018
  7. An Acellular Biologic Scaffold Promotes Skeletal Muscle Formation in Mice and Humans with Volumetric Muscle Loss Science Translational Medicine, 2014
  8. Mesenchymal Stem Cells: Identification, Phenotypic Characterization, Biological Properties and Potential for Regenerative Medicine through Biomaterial Micro-Engineering of Their Niche Methods, 2016
  9. Stem Cells and Healthy Aging Science, 2015
  10. Extracellular Matrix Bioscaffolds in Tissue Remodeling and Morphogenesis Developmental Dynamics, 2015
  11. Biologic Scaffolds for Regenerative Medicine: Mechanisms of In vivo Remodeling Annals of Biomedical Engineering, 2014
  12. Cell-Derived Matrices for Tissue Engineering and Regenerative Medicine Applications Biomaterials Science, 2015
  13. Sexual Dimorphism in Stem Cell-Based Therapies for the Musculoskeletal System Operative Techniques in Orthopaedics, 2016
  14. Cell-Derived Extracellular Matrix: Basic Characteristics and Current Applications in Orthopedic Tissue Engineering Tissue Engineering Part B: Reviews, 2016
  15. Biomaterials Control of Pluripotent Stem Cell Fate for Regenerative Therapy Progress in Materials Science, 2016
  16. Intracerebral Cell Implantation: Preparation and Characterization of Cell Suspensions Cell Transplantation, 2016
  17. Stem Cells in Skeletal Tissue Engineering: Technologies and Models  Current Stem Cell Research and Therapy, 2016
  18. Synergizing Engineering and Biology to Treat and Model Skeletal Muscle Injury and Disease Annual Review of Biomedical Engineering, 2015
  19. Youtube Video Collection on Tissue Engineering and Cellular Therapeutics

AR3T has a Mechanotransductive Core that has expertise in this area, with researchers who are available to provide consultations.

  1. NEW! Real-Time Monitoring of Mechanical Cues in the Regenerative Niche Reveal Dynamic Strain Magnitudes that Enhance Bone Repair bioRxiv, 2019
  2. Soft Tissue Manipulation: A Powerful Form of Mechanotherapy Journal of Physiotherapy and Physical Rehabilitation, 2016
  3. Biomechanical Stimulus Based Strategies for Meniscus Tissue Engineering and Regeneration Tissue Engineering Part B: Reviews, 2018
  4. Enhanced Neural Stem Cell Functions in Conductive Annealed Carbon Nanofibrous Scaffolds with Electrical Stimulation Nanomedicine: Nanotechnology, Biology and Medicine, 2018
  5. A Guide for Using Mechanical Stimulation to Enhance Tissue-Engineered Articular Cartilage Properties Tissue Engineering Part B: Reviews, 2018
  6. Understanding Mechanobiology: Physical Therapists as a Force in Mechanotherapy and Musculoskeletal Regenerative Rehabilitation  Physical Therapy, 2016
  7. Mechanotransduction: Relevance to Physical Therapist Practice—Understanding Our Ability to Affect Genetic Expression Through Mechanical Forces Physical Therapy, 2016
  8. Force Transmission in Epithelial Tissues Developmental Dynamics, 2016
  9. Substrate Stiffness Controls Osteoblastic and Chondrocytic Differentiation of Mesenchymal Stem Cells without Exogenous Stimuli PLOS ONE, 2017
  10. Mechanical and Vascular Cues Synergistically Enhance Osteogenesis in Human Mesenchymal Stem Cells  Tissue Engineering Part A, 2016
  11. Asymmetrical Seeding of MSCs into Fibrin–Poly(Ester-Urethane) Scaffolds and Its Effect on Mechanically Induced Chondrogenesis Journal of Tissue Engineering and Regenerative Medicine, 2016
  12. Gene Therapy for Inherited Muscle Diseases: Where Genetics Meets Rehabilitation Medicine American Journal of Physical Medicine and Rehabilitation, 2014
  13. Youtube video collection on Mechanobiology and Mechanotransduction
  14. Cell Mechanosensitivity to Extremely Low-Magnitude Signals is Enabled by a LINCed Nucleus Stem Cells, 2015
  15. Concise Review: Plasma and Nuclear Membranes Convey Mechanical Information to Regulate Mesenchymal Stem Cell Lineage Stem Cells, 2016
  16. The Nucleus is a Conserved Mechanosensation and Mechanoresponse Organelle Cytoskeleton, 2016
  17. Bone and Skeletal Muscle: Key Players in Mechanotransduction and Potential Overlapping Mechanisms Bone, 2015

AR3T supports technology development for this purpose.

  1. NEW! Real-Time Monitoring of Mechanical Cues in the Regenerative Niche Reveal Dynamic Strain Magnitudes that Enhance Bone Repair bioRxiv, 2019
  2. NEW! Minimally Invasive Muscle Embedding (MIME) – A Novel Experimental Technique to Facilitate Donor-Cell-Mediated Myogenesis Journal of Visualized Experiments, 2018
  3. NEW! Production of Elastin-like Protein Hydrogels for Encapsulation and Immunostaining of Cells in 3D Journal of Visualized Experiments, 2018
  4. Translation of Remote Control Regenerative Technologies for Bone Repair npj Regenerative Medicine, 2018
  5. Wearable Bioreactor Heralds Leap for Regenerative Medicine The Engineer, 2018
  6. EGaIn‐Assisted Room‐Temperature Sintering of Silver Nanoparticles for Stretchable, Inkjet‐Printed, Thin‐Film Electronics Advanced Materials, 2018
  7. Microfluidic Flow Cell Array for Controlled Cell Deposition in Engineered Musculoskeletal Tissues Tissue Engineering Part C: Methods, 2018
  8. Production of Elastin-like Protein Hydrogels for Encapsulations and Immunostaining of Cells in 3D Journal of Visualized Experiments, 2018
  9. Murine Model of Robotic Training to Evaluate Skeletal Muscle Recovery After Injury Medicine and Science in Sports and Exercise, 2017
  10. Substrate Stiffness Controls Osteoblastic and Chondrocytic Differentiation of Mesenchymal Stem Cells without Exogenous Stimuli PLOS ONE, 2017
  11. A Bird’s Eye View on the Use of Electrospun Nanofibrous Scaffolds for Bone Tissue Engineering: Current State-of-the-Are, Emerging Directions and Future Trends Nanomedicine: Nanotechnology, Biology and Medicine, 2016
  12. High Throughput Screening for Discovery of Materials That Control Stem Cell Fate Current Opinion in Solid State and Materials Science, 2016
  13. A Review of Three-Dimensional Printing in Tissue Engineering Tissue Engineering Part B: Reviews, 2016
  14. Advanced Imaging Approaches for Regenerative Medicine: Emerging Technologies for Monitoring Stem Cell Fate In Vitro and In Vivo Biotechnology Journal, 2015
  15. Electrodiagnostic Evaluation of Individuals Implanted With Extracellular Matrix for the Treatment of Volumetric Muscle Injury: Case Series Physical Therapy, 2016
  16. Youtube video collection on Regenerative Medicine research technology
    1. Minimally Invasive Muscle Embedding (MIME) – A Novel Experimental Technique to Facilitate Donor-Cell-Mediated Myogenesis  Journal of Visualized Experiments, 2017
    2. Cytokine Networks in Immune-Mediated Muscle Regeneration Journal of Immunology and Regenerative Medicine, 2018
    3.  Concise Review: Musculoskeletal Stem Cells to Treat Age-Related Osteoporosis Stem Cells Translational Medicine, 2017
    4. Mesenchymal Stem Cells: Identification, Phenotypic Characterization, Biological Properties and Potential for Regenerative Medicine through Biomaterial Micro-Engineering of Their Niche Methods, 2016
    5. Youtube Video Collection on the Topic of Regenerative Medicine
    6. Regenerative Medicine and Regenerative Rehabilitation Podcast collection
      1. Dr. Fabrisia Ambrosio -Regenerative Rehabilitation #97
      2. Dr. Tom Rando -muscle stem cell biology #111
      3. Dr. Steve Wolf  -Regenerative Rehabilitation and educating clinicians #112
      4. Dr. George Christ -musculoskeletal tissue engineering #115
      5. Dr. Michel Modo -stem cell therapy, neuroimaging and stroke #117
      6. Dr. Ravi Bellamkonda -nerve gap repair #121
      7. Dr. Jonathan Cheetham -TE for larynx, nasopharynx and trachea #124
      8. Dr. Linda Noble- Haeusslein -CNS injuries #129
      9. Dr. David Borton -spinal injuries and Regenerative Rehabilitation #133
      10. Patrick Cantini -muscle tissue engineering study #141
      11. Dr. Stephen Badylak –npj Regenerative Medicine #154
      12. Dr. Michael Boninger -Regenerative Rehabilitation #155
      13. Dr. Elisabeth Barton -skeletal muscle repair #158
      14. Dr. Rocky Tuan -musculoskeletal disorders #166
      15. Drs. Lorenzo Soletti and Bryan Brown -peripheral nerve repair #175
      16. Dr. Antonio D’Amore -artificial heart valves and cardiac patches #178
      17. Dr. Fatima Syed-Picard -craniofacial tissue engineering #179
      18. Dr. Stephen Badylak –Journal of Immunology and Regenerative Medicine #182
  1. American Regenerative Rehabilitation and GenomicsAcademy of Physical Medicine and Rehabilitation (AAPM&R)
  2. American Physical Therapy Association (APTA)
  3. International Society for Stem Cell Research
  4. McGowan Institute for Regenerative Medicine
  5. Medical Rehabilitation Research Resource Network (MR3)
  6. RegenerativeMedicine.net
  7. RegMedNet: At RegMedNet we truly believe that regenerative medicine is going to revolutionize modern healthcare. The field comprises a multidisciplinary mix of experts, from regulators to manufacturers to researchers: RegMedNet is a networking site that unites all members of the diverse regenerative medicine community, enabling them to share the latest news, inspiration and insights, and connect and collaborate in order to help this exciting field move forward at an even faster rate.