Publications and Resources

Publications and Resources2019-06-07T14:40:30+00:00

Click each heading to find a list of publications and resources.

  1. NEW! Recreating embryonic conditions at break sites can help bones heal faster
  2. NEW! Regenerative rehabilitation of the musculoskeletal system
  3.  The convergence of regenerative medicine and rehabilitation: federal perspectives
  4.  The regenerative rehabilitation collection: a forum for an emerging field
  5.  Rehabilitation following regenerative medicine treatment for knee osteoarthritis-current concept review
  6. Regenerative Rehabilitation: The Role of Mechanotransduction in Orthopaedic Regenerative Medicine 
  7.  Regenerative Rehabilitation: Applied Biophysics Meets Stem Cell Therapeutics
  8.  Regenerative Rehabilitation: Combining Stem Cell Therapies and Activity Dependent Simulation
  9. Cellular Rehab: Physical therapy and exercise are critical to the success of cell therapies approaching the clinic.
  10. Regenerative Rehabilitation: A New Future?
  11. Opportunities for Regenerative Rehabilitation and Advanced Technologies in Physical Therapy: Perspective From Academia.
  12. The Role of PTs in Regenerative Medicine
  13. The Role of Physiatry in Regenerative Medicine: The Past, The Present, and Future Challenges
  14. Regenerative Rehabilitation and Genomics: Frontiers in Clinical Practice.
  15. Neural Stem Cell Therapy and Rehabilitation in the Central Nervous System: Emerging Partnerships
  16. Developmental Biology and Regenerative Medicine: Addressing the Vexing Problem of Persistent Muscle Atrophy in the Chronically Torn Human Rotator Cuff
  17. Regenerative Principles Enrich Cardiac Rehabilitation Practice
  18. Emergent Themes from Second Annual Symposium on Regenerative Rehabilitation, Pittsburgh, Pennsylvania
  19. Toward a Convergence of Regenerative Medicine, Rehabilitation, and Neuroprosthetics
  20. The Emerging Relationships between Regenerative Medicine and Physical Therapeutics
  21. Regenerative Rehabilitation: A Call To Action
  22. Youtube video collection on Regenerative Rehabilitation
  1. NEW! PGC-1α overexpression partially rescues impaired oxidative and contractile pathophysiology following volumetric muscle loss injury
  2. NEW! Production of elastin-like protein hydrogels for encapsulation and immunostaining of cells in 3D
  3. NEW! Rehabilitative exercise and spatially patterned nanofibrillar scaffolds enhance vascularization and innervation following volumetric muscle loss
  4. NEW! Aligned nanofibrillar scaffolds for controlled delivery of modified mRNA
  5. NEW! Engineering Biomimetic Materials for skeletal muscle repair and regeneration
  6. NEW! Extracellular matrix remodelling induced by alternating electrical and mechanical stimulations increases the contraction of engineered skeletal muscle tissues
  7. Translation of remote control regenerative technologies for bone repair
  8. Rehabilitative exercise and spatially patterned nanofibrillar scaffolds enhance vascularization and innervation following volumetric muscle loss
  9. Effectiveness of mesenchymal stem cells for treating patients with knee osteoarthritis: a meta-analysis toward the establishment of effective regenerative rehabilitation
  10. Environmental Influences on Stem Cell Behavior
  11. Early Rehabilitation for Volumetric Muscle Loss Injury Augments Regenerative Aspects of Muscle Strength and Oxidative Capacity 
  12. Bioengineered Constructs Combined with Exercise Enhance Stem Cell-Mediated Treatment of Volumetric Muscle Loss
  13. Biological Effects of Dosing Aerobic Exercise and Neuromuscular Electrical Stimulation in Rats
  14. Targeted Rehabilitation After Extracellular Matrix Scaffold Transplantation for the Treatment of Volumetric Muscle Loss
  15. Neuromuscular Electrical Stimulation as a Method to Maximize the Beneficial Effects of Muscle Stem Cells Transplanted into Dystrophic Skeletal Muscle
  16. The Synergistic Effect of Treadmill Running on Stem-Cell Transplantation to Heal Injured Skeletal Muscle
  17. Interactive Effects of Cell Therapy and Rehabilitation Realize the Full Potential of Neurogenesis in Brain Injury Model
  18. Gene Therapy for Inherited Muscle Diseases: Where Genetics Meets Rehabilitation Medicine
  19. Regenerative and Rehabilitative Medicine: A Necessary Synergy for Functional Recovery from Volumetric Muscle Loss Injury

AR3T has a Cellular Therapeutics/Tissue Engineering Core that has expertise and training in this area, with researchers who are available for consultations.

  1. NEW! Damaged muscle fibers might masquerade as hybrid fibers – a cautionary note on immunophenotyping mouse muscle with mouse monoclonal antibodies
  2. NEW! In Vitro Repair of Meniscal Radial Tear With Hydrogels Seeded With Adipose Stem Cells and TGF-β3
  3. NEW! Engineering Biomimetic Materials for Skeletal Muscle Repair and Regeneration
  4. NEW! Aligned Nanofibrillar Scaffolds for Controlled Delivery of Modified mRNA
  5. Regenerative Rehabilitation of the Musculoskeletal System
  6. Production of Elastin-like Protein Hydrogels for Encapsulations and Immunostaining of Cells in 3D
  7. An Acellular Biologic Scaffold Promotes Skeletal Muscle Formation in Mice and Humans with Volumetric Muscle Loss
  8. Mesenchymal Stem Cells: Identification, Phenotypic Characterization, Biological Properties and Potential for Regenerative Medicine through Biomaterial Micro-Engineering of Their Niche
  9. Stem Cells and Healthy Aging
  10. Extracellular Matrix Bioscaffolds in Tissue Remodeling and Morphogenesis
  11. Biologic Scaffolds for Regenerative Medicine: Mechanisms of In vivo Remodeling
  12. Cell-Derived Matrices for Tissue Engineering and Regenerative Medicine Applications
  13. Sexual Dimorphism in Stem Cell-Based Therapies for the Musculoskeletal System
  14. Cell-Derived Extracellular Matrix: Basic Characteristics and Current Applications in Orthopedic Tissue Engineering
  15. Biomaterials Control of Pluripotent Stem Cell Fate for Regenerative Therapy
  16. Intracerebral Cell Implantation: Preparation and Characterization of Cell Suspensions
  17. Stem Cells in Skeletal Tissue Engineering: Technologies and Models
  18. Synergizing Engineering and Biology to Treat and Model Skeletal Muscle Injury and Disease
  19. Youtube video collection on Tissue Engineering and Cellular Therapeutics

AR3T has a Mechanotransductive Core that has expertise in this area, with researchers who are available to provide consultations.

  1. NEW! Real-time monitoring of mechanical cues in the regenerative niche reveal dynamic strain magnitudes that enhance bone repair
  2. Soft Tissue Manipulation: A Powerful Form of Mechanotherapy
  3. Biomechanical Stimulus Based Strategies for Meniscus Tissue Engineering and Regeneration
  4. Enhanced Neural Stem Cell Functions in Conductive Annealed Carbon Nanofibrous Scaffolds with Electrical Stimulation
  5. A Guide for Using Mechanical Stimulation to Enhance Tissue-Engineered Articular Cartilage Properties
  6. Understanding Mechanobiology: Physical Therapists as a Force in Mechanotherapy and Musculoskeletal Regenerative Rehabilitation
  7. Mechanotransduction: Relevance to Physical Therapist Practice—Understanding Our Ability to Affect Genetic Expression Through Mechanical Forces
  8. Force Transmission in Epithelial Tissues
  9. Substrate Stiffness Controls Osteoblastic and Chondrocytic Differentiation of Mesenchymal Stem Cells without Exogenous Stimuli
  10. Mechanical and Vascular Cues Synergistically Enhance Osteogenesis in Human Mesenchymal Stem Cells
  11. Asymmetrical Seeding of MSCs into Fibrin–Poly(Ester-Urethane) Scaffolds and Its Effect on Mechanically Induced Chondrogenesis
  12. Gene Therapy for Inherited Muscle Diseases: Where Genetics Meets Rehabilitation Medicine
  13. Youtube video collection on Mechanobiology and Mechanotransduction
  14. Cell Mechanosensitivity to Extremely Low-Magnitude Signals is Enabled by a LINCed Nucleus
  15. Concise Review: Plasma and Nuclear Membranes Convey Mechanical Information to Regulate Mesenchymal Stem Cell Lineage
  16. The Nucleus is a Conserved Mechanosensation and Mechanoresponse Organelle
  17. Bone and Skeletal Muscle: Key Players in Mechanotransduction and Potential Overlapping Mechanisms

AR3T supports technology development for this purpose.

  1. NEW! Real-time monitoring of mechanical cues in the regenerative niche reveal dynamic strain magnitudes that enhance bone repair
  2. NEW! Minimally Invasive Muscle Embedding (MIME) – A Novel Experimental Technique to Facilitate Donor-Cell-Mediated Myogenesis
  3. NEW! Production of Elastin-like Protein Hydrogels for Encapsulation and Immunostaining of Cells in 3D
  4. Translation of remote control regenerative technologies for bone repair
  5. Wearable bioreactor heralds leap for regenerative medicine
  6. EGaIn‐Assisted Room‐Temperature Sintering of Silver Nanoparticles for Stretchable, Inkjet‐Printed, Thin‐Film Electronics
  7. Microfluidic Flow Cell Array for Controlled Cell Deposition in Engineered Musculoskeletal Tissues
  8. Production of Elastin-like Protein Hydrogels for Encapsulations and Immunostaining of Cells in 3D
  9. Murine Model of Robotic Training to Evaluate Skeletal Muscle Recovery After Injury
  10. Substrate Stiffness Controls Osteoblastic and Chondrocytic Differentiation of Mesenchymal Stem Cells without Exogenous Stimuli
  11. A Bird’s Eye View on the Use of Electrospun Nanofibrous Scaffolds for Bone Tissue Engineering: Current State-of-the-Are, Emerging Directions and Future Trends
  12. High Throughput Screening for Discovery of Materials That Control Stem Cell Fate
  13. A Review of Three-Dimensional Printing in Tissue Engineering
  14. Advanced Imaging Approaches for Regenerative Medicine: Emerging Technologies for Monitoring Stem Cell Fate In Vitro and In Vivo
  15. Electrodiagnostic Evaluation of Individuals Implanted With Extracellular Matrix for the Treatment of Volumetric Muscle Injury: Case Series
  16. Youtube video collection on Regenerative Medicine research technology
    1. Minimally Invasive Muscle Embedding (MIME) – A Novel Experimental Technique to Facilitate Donor-Cell-Mediated Myogenesis 
    2. Cytokine Networks in Immune-Mediated Muscle Regeneration
    3.  Concise Review: Musculoskeletal stem cells to treat age-related osteoporosis
    4. Mesenchymal Stem Cells: Identification, Phenotypic Characterization, Biological Properties and Potential for Regenerative Medicine through Biomaterial Micro-Engineering of Their Niche
    5. Youtube video collection on the topic of Regenerative Medicine
    6. Regenerative Medicine and Regenerative Rehabilitation Podcast collection
      1. Dr. Fabrisia Ambrosio -Regenerative Rehabilitation #97
      2. Dr. Tom Rando -muscle stem cell biology #111
      3. Dr. Steve Wolf  -Regenerative Rehabilitation and educating clinicians #112
      4. Dr. George Christ -musculoskeletal tissue engineering #115
      5. Dr. Michel Modo -stem cell therapy, neuroimaging and stroke #117
      6. Dr. Ravi Bellamkonda -nerve gap repair #121
      7. Dr. Jonathan Cheetham -TE for larynx, nasopharynx and trachea #124
      8. Dr. Linda Noble- Haeusslein -CNS injuries #129
      9. Dr. David Borton -spinal injuries and Regenerative Rehabilitation #133
      10. Patrick Cantini -muscle tissue engineering study #141
      11. Dr. Stephen Badylak –npj Regenerative Medicine #154
      12. Dr. Michael Boninger -Regenerative Rehabilitation #155
      13. Dr. Elisabeth Barton -skeletal muscle repair #158
      14. Dr. Rocky Tuan -musculoskeletal disorders #166
      15. Drs. Lorenzo Soletti and Bryan Brown -peripheral nerve repair #175
      16. Dr. Antonio D’Amore -artificial heart valves and cardiac patches #178
      17. Dr. Fatima Syed-Picard -craniofacial tissue engineering #179
      18. Dr. Stephen Badylak –Journal of Immunology and Regenerative Medicine #182
  1. American Regenerative Rehabilitation and GenomicsAcademy of Physical Medicine and Rehabilitation (AAPM&R)
  2. American Physical Therapy Association (APTA)
  3. International Society for Stem Cell Research
  4. McGowan Institute for Regenerative Medicine
  5. Medical Rehabilitation Research Resource Network (MR3)
  6. RegenerativeMedicine.net
  7. RegMedNet: At RegMedNet we truly believe that regenerative medicine is going to revolutionize modern healthcare. The field comprises a multidisciplinary mix of experts, from regulators to manufacturers to researchers: RegMedNet is a networking site that unites all members of the diverse regenerative medicine community, enabling them to share the latest news, inspiration and insights, and connect and collaborate in order to help this exciting field move forward at an even faster rate.